Absorption in the Digestive System

When you consume a cannabis edible, it passes through the digestive system. The edible is broken down in the stomach and then moves into the small intestine, where the cannabinoids, such as THC and CBD, are absorbed into the bloodstream. This process takes longer compared to inhalation methods, as the cannabinoids need to be metabolized by the liver before entering the bloodstream.

Conversion of THC to 11-Hydroxy-THC

Once in the liver, THC undergoes a process called first-pass metabolism. It is converted into a more potent compound called 11-hydroxy-THC. This conversion contributes to the unique effects of edibles, which are often described as more intense and longer-lasting compared to other consumption methods.

Time to Onset and Duration

The onset time for the effects of cannabis edibles can vary significantly compared to inhalation methods. It typically takes anywhere from 30 minutes to 2 hours for the effects to be felt, as the cannabinoids go through the digestive and metabolic processes. The effects can last for several hours, with peak intensity occurring within the first 2-4 hours.

Factors Affecting Absorption and Effects

Several factors can influence the absorption and effects of cannabis edibles. These include the individual's metabolism, body weight, tolerance, and the presence of food in the stomach. Consuming edibles on an empty stomach may result in faster absorption and stronger effects, while consuming them with a meal can slow down the onset and reduce the intensity.

Dosing and Effects

Dosing is crucial when it comes to cannabis edibles. The potency of edibles is measured in milligrams of THC or CBD per serving. It is recommended to start with a low dose, typically 2-5 milligrams, and wait at least 2 hours before consuming more. This allows time to assess the effects and prevent overconsumption, which can lead to unpleasant experiences.

Safety and Responsible Consumption

It is important to consume cannabis edibles responsibly and in a safe environment. Start low and go slow, allowing enough time for the effects to manifest before deciding to consume more. Always store edibles securely, away from children and pets, and be aware of local laws and regulations regarding cannabis consumption.

In conclusion, understanding the science behind cannabis edibles can help us make informed choices and have a better understanding of how they are processed in the body. From absorption in the digestive system to the conversion of THC and the factors influencing onset and duration, there is a fascinating interplay between cannabinoids and our physiology. By approaching cannabis edibles with knowledge and responsible consumption practices, we can fully enjoy their unique effects and benefits.